NCAPD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110016-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5110016 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NCAPD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NCAPD2
Gene Alias
2810406C15Rik; 2810465G24Rik; Capd2; CAP-D2; chromosome condensation related SMC associated protein 1; chromosome condensation-related SMC-associated protein 1; Chromosome-associated protein D2; CNAP1; Condensin complex subunit 1; hCAP-D2; KIAA0159; mCAP-D2; mKIAA0159; Ncapd2; Non-SMC condensin I complex subunit D2; non-SMC condensin I complex, subunit D2; RGD1562596; XCAP-D2 homolog
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
362438, 68298, 9918
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.29 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q15021, Q8K2Z4
Gene Symbols
NCAPD2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1250-1350 of human NCAPD2 (NP_0556803)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: FGDKLSDESI FSAFLSVVGK LRRGAKPEGK AIIDEFEQKL RACHTRGLDG IKELEIGQAG SQRAPSAKKP STGSRYQPLA STASDNDFVT PEPRRTTRRH P Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes
- The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases
- May target the condensin complex to DNA via its C-terminal domain (PubMed:11136719)
- May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids
- Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation
- Required for decatenation of non-centromeric μgtrafine DNA bridges during anaphase
- Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, μgtimately affecting neuron pool and cortex size (PubMed:27737959)
- [UniProt]