PIPA5112385

CHKB Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112385-Each-of-1 In Stock ₹ 43,476.50

PIPA5112385 - Each of 1

₹ 43,476.50

In Stock

Quantity

1

Base Price: ₹ 43,476.50

GST (18%): ₹ 7,825.77

Total Price: ₹ 51,302.27

Antigen

CHKB

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CHKB

Gene Alias

Chetk; CHKB; Chkl; choline kinase beta; Choline kinase-like protein; choline/ethanolamine kinase; choline/ethanolamine kinase beta; choline/ethanolamine kinase-b; choline/ethanolaminekinase; CK; Ck/Ek; Ck/Ek-beta; CKB; CKEKB; EK; EKB; ethanolamine kinase; Ethanolamine kinase beta; MDCMC

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1120, 12651, 29367

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

3.34 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

O54783, O55229, Q9Y259

Gene Symbols

CHKB

Immunogen

Recombinant Human Choline/ethanolamine kinase protein (2-99AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway
  • Choline kinase, the initial enzyme in the sequence, plays a role in cell growth proliferation
  • A related protein, ChoKB (also, known as choline kinase beta), is a 395 amino acid enzyme that catalyzes the phosphorylation of choline by ATP in the presence of magnesium, thereby yielding phosphocholine and ADP
  • Like all choline kinases, ChoKB possesses ethanoalamine kinase activity and catalyzes the phosphorylation of ethanolamine
  • The gene encoding ChoKB is located less than 1 kb upstream of the CPT1B gene, suggesting that the ChoKB gene may regulate transcription CPT1B
  • In mice, mutations and/or deletions in the gene encoding ChoKB are the cause of hindlimb muscular dystrophy and neonatal bone deformity.