PIPA5112885

AMPK beta-2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112885-Each-of-1 In Stock ₹ 43,120.50

PIPA5112885 - Each of 1

₹ 43,120.50

In Stock

Quantity

1

Base Price: ₹ 43,120.50

GST (18%): ₹ 7,761.69

Total Price: ₹ 50,882.19

Antigen

AMPK beta-2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Prkab2

Gene Alias

5730553K21Rik; 5'-AMP-activated protein kinase subunit beta-2; 5'-AMP-activated protein kinase, beta-2 subunit; AMP-activated protein kinase beta 2 non-catalytic subunit; AMP-activated protein kinase beta-2 regulatory subunit; AMPK beta 2; AMPK beta-2 chain; AMPK subunit beta-2; AMPKbeta2; AW049591; BB124140; Prkab2; protein kinase AMP-activated non-catalytic subunit beta 2; protein kinase, AMP-activated, beta 2 non-catalytic subunit

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

108097, 5565, 64562

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Western Blot

Concentration

0.43 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O43741, Q6PAM0, Q9QZH4

Gene Symbols

Prkab2

Immunogen

Recombinant Human 5'-AMP-activated protein kinase subunit beta-2 protein (1-272AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • AMPK Beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK)
  • AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits
  • AMPK is an important energy-sensing enzyme that monitors cellular energy status
  • In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol
  • This subunit may be a positive regulator of AMPK activity
  • The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK
  • This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.