AMPK alpha-2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596645-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA596645 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
AMPK alpha-2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PRKAA2
Gene Alias
2310008I11Rik, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase, catalytic alpha-2 chain, A830082D05, ACACA kinase, Acetyl-CoA carboxylase kinase, AMP-activated protein kinase, AMP-activated protein kinase alpha-2 subunit variant 2, AMP-activated protein kinase alpha-2 subunit variant 3, AMP-activated protein kinase alpha-2 variant B, AMPK, AMPK alpha 2, AMPK alpha-2 chain, AMPK subunit alpha-2, AMPK2, AMPKa2, AMPKalpha2, AMPK-alpha-2 chain, EC 2.7.11.1, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, PRKAA, Prkaa2, protein kinase AMP-activated catalytic subunit alpha 2, protein kinase, AMP-activated, alpha 2 catalytic subunit
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
108079, 5563, 78975
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.56 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P54646, Q09137, Q8BRK8
Gene Symbols
PRKAA2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 270-343 of human AMPKalpha2 (NP_0062432)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: SW620, NCI-H460, Mouse brain, Mouse heart, Rat skeletal muscle; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: QDLPSYLFPE DPSYDANVID DEAVKEVCEK FECTESEVMN SLYSGDPQDQ LAVAYHLIID NRRIMNQASE FYLA The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK)
- AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits
- AMPK is an important energy-sensing enzyme that monitors cellular energy status
- In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol
- Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.