PIPA595312

AMPK beta-1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595312-Each-of-1 In Stock ₹ 46,502.50

PIPA595312 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

AMPK beta-1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRKAB1

Gene Alias

1300015D22Rik, 5'-AMP-activated protein kinase 40 kDa subunit, 5-AMP-activated protein kinase beta subunit, 5'-AMP-activated protein kinase beta-1 subunit, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit beta-1-like protein, 5'-AMP-activated protein kinase, beta subunit, AAKB1, AMP-activated protein kinase beta subunit, AMPK, AMPK beta 1, AMPK beta -1 chain, AMPK beta-1 chain, AMPK subunit beta-1, AMPKb, AMPK-beta1, AU021155, E430008F22, HAMPKb, kinase AMPK-beta1, kinase pAMPK, pAMPK, Prkab1, protein kinase AMP-activated non-catalytic subunit beta 1, protein kinase, AMP-activated, beta 1 non-catalytic subunit, protein kinase, AMP-activated, noncatalytic, beta-1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5564

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Immunocytochemistry, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

Q9Y478

Gene Symbols

PRKAB1

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human AMPK beta 1 (32-68aa DRPKILMDSPEDADLFHSEEIKAPEKEEFLAWQHDLE).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK)
  • AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits
  • AMPK is an important energy-sensing enzyme that monitors cellular energy status
  • In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol
  • This subunit may be a positive regulator of AMPK activity
  • The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK
  • This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.