INSR Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115426-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5115426 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
INSR
Classification
Polyclonal
Conjugate
Unconjugated
Gene
INSR
Gene Alias
4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3643
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P06213
Gene Symbols
INSR
Immunogen
A synthesized peptide derived from human INSR(Accession P06213), corresponding to amino acid residues L1329-S1379.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total IR
- INSR is a receptor tyrosine kinase
- Binding of insulin to the extracellular domain of INSR stimulates glucose uptake
- INSR and IGF-1 receptors share major structural and functional similarity
- The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR
- In humans, the INSR gene is located on chromosome 19
- Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.