PIPA5116821

MLLT1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116821-Each-of-1 In Stock ₹ 46,502.50

PIPA5116821 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MLLT1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MLLT1

Gene Alias

AA407901; BAM11; CTC-503J8.6; ENL; ENL/MLL fusion; leukemia-associated protein MLLT1; LTG19; MLL/ENL fusion protein; MLLT1; MLLT1 super elongation complex subunit; MLLT1, super elongation complex subunit; MLLT1/MLL fusion; myeloid/lymphoid or mixed lineage leukemia translocation to 1 homolog; myeloid/lymphoid or mixed lineage-leukemia translocation to 1 homolog; myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1; protein ENL; trithorax; YEATS domain-containing protein 1; YEATS1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

301119, 4298, 64144

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.85 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

Q03111

Gene Symbols

MLLT1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-270 of human MLLT1 (NP_0059252)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: Mouse thymus, Rat brain, Rat thymus Immunogen sequence: KTSKPHKVTK EHRERPRKDS ESKSSSKELE REQAKSSKDT SRKLGEGRLP KEEKAPPPKA AFKEPKMALK ETKLESTSPK G Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia
  • The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins
  • Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias
  • The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.