PTPRS Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121660-Each-of-1 | In Stock | ₹ 17,346.10 |
PIPA5121660 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,346.10
GST (18%): ₹ 3,122.298
Total Price: ₹ 20,468.398
Antigen
PTPRS
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ptprs
Gene Alias
AL022616; Larptp2; LAR-PTP2; Leukocyte common antigen-related protein-tyrosine phosphatase 2; leukocyte common antigen-related proten-tyrosine phosphatase 2; protein tyrosine phosphatase PTPsigma; protein tyrosine phosphatase, receptor type S; protein tyrosine phosphatase, receptor type, D; protein tyrosine phosphatase, receptor type, S; PTP; PTP-NU3; PTPNU-3; Ptprd; Ptprs; PTPsigma; Ptpsigma.; Ptpt9; Receptor-type tyrosine-protein phosphatase S; Receptor-type tyrosine-protein phosphatase sigma; Rptpd; R-PTP-S; RPTPsigma; R-PTP-sigma; tissue-specific protein tyrosine phosphatase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19280
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.64 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
B0V2N1
Gene Symbols
Ptprs
Immunogen
Recombinant protein Tyrosine Phosphatase Receptor Type S. The antigen corresponds to amino acid range 889-1102 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PTPRS cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan
- Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth
- Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection
- Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2
- Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb
- Functions as tyrosine phosphatase
- Mediates dephosphorylation of NTRK1, NTRK2 and NTRK3
- Plays a role in down-regulation of signaling cascades that lead to the activation of Akt and MAP kinases
- Down-regulates TLR9-mediated activation of NF-kappa-B, as well as production of TNF, interferon alpha and interferon beta.