PIPA5143383

B-Raf (K601E Mutant) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143383-Each-of-1 In Stock ₹ 39,427.00

PIPA5143383 - Each of 1

₹ 39,427.00

In Stock

Quantity

1

Base Price: ₹ 39,427.00

GST (18%): ₹ 7,096.86

Total Price: ₹ 46,523.86

Antigen

B-Raf (K601E Mutant)

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

B-raf; B-Raf proto-oncogene, serine/threonine kinase; BRAF1; B-RAF1; NS7; RAFB1

Immunogen

Carrier-protein conjugated synthetic peptide surrounding mutant K601E of human B-Raf. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.54 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases|This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion|Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung|Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes|A pseudogene of this gene has been identified on the X chromosome