PIPA5143768

SMPD4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143768-Each-of-1 In Stock ₹ 45,879.50

PIPA5143768 - Each of 1

₹ 45,879.50

In Stock

Quantity

1

Base Price: ₹ 45,879.50

GST (18%): ₹ 8,258.31

Total Price: ₹ 54,137.81

Antigen

SMPD4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SMPD4

Gene Alias

4122402O22Rik; Kiaa1418; mKIAA1418; NET13; neutral membrane (neutral sphingomyelinase-3); neutral sphingomyelinase 3; Neutral sphingomyelinase III; neutral sphingomyelinase-3; NSMASE3; nSMase-3; RGD1310674; SKNY; SKNY protein; Smpd4; Sphingomyelin phosphodiesterase 4; sphingomyelin phosphodiesterase 4, neutral membrane; sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

303790, 55627, 77626

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

Q6ZPR5, Q9NXE4

Gene Symbols

SMPD4

Immunogen

nSMase3 synthetic peptide corresponds to amino acids in the C-terminal region of mouse nSMase3. This sequence is highly conserved in rat and human nSMase3, and has low homology to other nSMase family members.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • The antibody detects an 85-90 kDa* band corresponding to nSMase3 on SDS-PAGE immunoblots of adult mouse heart and mouse C2C12 cells
  • The antibody works for western blot, ELISA, immunoprecipitation, and immunocytochemistry
  • The protein encoded by SMPD4 is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide
  • This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53
  • The encoded protein localizes to the endoplasmic reticulum and Golgi network.