Phospho-SSH1 (Ser978) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143766-Each-of-1 | In Stock | ₹ 45,879.50 |
PIPA5143766 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,879.50
GST (18%): ₹ 8,258.31
Total Price: ₹ 54,137.81
Antigen
Phospho-SSH1 (Ser978)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SSH1
Gene Alias
hSSH-1L; KIAA1298; Protein phosphatase Slingshot homolog 1; slingshot homolog 1; slingshot protein phosphatase 1; SSH1; SSH1L; SSH-1L; SSH-like protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
231637, 304580, 54434
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
Q76I79, Q8WYL5
Gene Symbols
SSH1
Immunogen
Slingshot-1L (Ser-978) antibody was generated from a phospho-peptide that included amino acids surrounding serine 978 in human SSH1L. This sequence has high homology to the conserved site in rat, mouse, chicken, and zebrafish SSH1L. The sequence also has high homology to the conserved site in SSH2L (Ser-1259).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Related Products
Description
- The antibody detects a 150 kDa* full length recombinant human SSH1L phosphoprotein and this reactivity is eliminated with lambda phosphatase treatment
- The antibody also detects SSH1L on immunoblots of rat PC12 and mouse C2C12 cells that were stimulated with calyculin A
- This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes
- The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin
- It possesses at least two conserved domains that could be important for its function
- First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus
- Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation
- It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions
- Two transcript variants encoding different isoforms have been found for this gene.