PIPA5143787

Phospho-VAV2 (Tyr142) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143787-Each-of-1 In Stock ₹ 45,879.50

PIPA5143787 - Each of 1

₹ 45,879.50

In Stock

Quantity

1

Base Price: ₹ 45,879.50

GST (18%): ₹ 8,258.31

Total Price: ₹ 54,137.81

Antigen

Phospho-VAV2 (Tyr142)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Vav2

Gene Alias

2810040F13Rik; AI847175; Guanine nucleotide exchange factor VAV2; Oncogene VAV2; vav 2 guanine nucleotide exchange factor; vav 2 oncogene; vav guanine nucleotide exchange factor 2; VAV2; VAV-2; Vav2 oncogene

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22325, 296603, 7410

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P52735, Q60992

Gene Symbols

Vav2

Immunogen

Phospho-Vav2 (Tyr-142) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-142 in mouse Vav2. This sequence has high homology with similar regions in rat and human Vav2, and has significant homology to the conserved site in Vav1 and Vav3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • This antibody was cross-adsorbed to unphosphorylated Vav2 (Tyr-142) peptide before affinity purification using phospho-Vav2 (Tyr-142) peptide (without carrier)
  • The antibody detects a 100 kDa* band corresponding to Vav on SDS-PAGE immunoblots of human A431 cells treated with EGF and detects Vav1, Vav2, and Vav3 in Jurkat cells treated with pervanadate
  • The antibody does not detect these Vavs after treatment with alkaline phosphatase
  • VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes
  • Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues
  • Alternatively spliced transcript variants encoding different isoforms have been found for this gene.