PIPA521322

RASSF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521322-Each-of-1 In Stock ₹ 46,591.50

PIPA521322 - Each of 1

₹ 46,591.50

In Stock

Quantity

1

Base Price: ₹ 46,591.50

GST (18%): ₹ 8,386.47

Total Price: ₹ 54,977.97

Antigen

RASSF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RASSF1

Gene Alias

123F protein; 123F2; AA536941; AU044980; cardiac-specific ras association domain family 1 protein; NORE2A; pancreas-specific ras association domain family 1 protein; protein 123F2; Ras association (RalGDS/AF-6) domain family 1; Ras association (RalGDS/AF-6) domain family member 1; Ras association domain family 1; Ras association domain family member 1; ras association domain-containing protein 1; Rassf1; Rassf1A; RASSF1A tumor suppressor; Rassf1B; Rassf1C; RDA32; REH3P21; tumor suppressor protein RDA32; wu:fc17f02; WUGSC:H_LUCA12.5; zgc:112224; zgc:92505; zgc:92505 protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11186

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9NS23

Gene Symbols

RASSF1

Immunogen

Recombinant fragment corresponding to a region within amino acids 50 and 344 of RASSF1 (Uniprot ID#Q9NS23)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, HeLaS3
  • Predicted reactivity: Mouse (92%), Rat (91%), Sheep (96%), Bovine (97%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • This gene encodes a protein similar to the RAS effector proteins
  • Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene
  • The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region
  • The encoded protein was found to interact with DNA repair protein XPA
  • The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest
  • Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.