PIPA525131
CNOT6L Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA525131-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA525131 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CNOT6L
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CNOT6L
Gene Alias
Carbon catabolite repressor protein 4 homolog B; CCR4b; CCR4-NOT transcription complex subunit 6 like; CCR4-NOT transcription complex subunit 6-like; CCR4-NOT transcription complex, subunit 6-like; CNOT6L
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
246175
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q96LI5
Gene Symbols
CNOT6L
Immunogen
KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human CNO6L
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with mouse and Xenopus based on sequence homology
- Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate
- Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation
- Additional complex functions may be a consequence of its influence on mRNA expression
- May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism
- Involved in deadenylation-dependent degradation of CDKN1B mRNA
- Its mRNA deadenylase activity can be inhibited by TOB1
- Mediates cell proliferation and cell survival and prevents cellular senescence
- [UniProt]