CRB2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA525628-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA525628 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
CRB2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CRB2
Gene Alias
5930402A21; BC043114; Crb2; crumbs 2; crumbs 2, cell polarity complex component; crumbs family member 2; crumbs homolog 2; crumbs2; crumbs-like protein 2; FSGS9; Protein crumbs homolog 2; RGD1309368; VMCKD
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
241324, 286204
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q5IJ48, Q80YA8
Gene Symbols
CRB2
Immunogen
KLH conjugated synthetic peptide between 1258-1285 amino acids from the C-terminal region of human CRUM2
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- CRB2 (Crumbs homolog 2), like its homologs CRB1 and CRB3, is similar to the Drosophila crumbs protein and is expressed in retina, brain and kidney
- Along with other proteins, the Crumbs proteins form a complex that help set up cell polarity in developing neuroepithelial cells
- At the onset of neural specification, embryonic stem cells (ESCs) upregulate CRB2, which then localizes apically in neural rosettes
- Gain- and loss-of-function studies of CRB2 have shown that CRB2 is essential for the stabilization of other polarity proteins
- Unlike CRB1, mutations in CRB2 do not appear to play a role in retinitis pigmentosa or in Leber congenital amaurosis.