PIPA589188

Thromboxane synthase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA589188-Each-of-1 In Stock ₹ 46,057.50

PIPA589188 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

Thromboxane synthase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TBXAS1

Gene Alias

BDPLT14, CYP5, Cyp5a1, cytochrome P450 5A1, cytochrome P450, family 5, subfamily A, polypeptide 1, FLJ52771, GHOSAL, platelet, cytochrome P450, subfamily V, similar to Thromboxane-A synthase (TXA synthase) (TXS), Tbxas1, THAS, ThromboxA ane synthase 1, thromboxane A synthase 1, thromboxane A synthase 1 (platelet), thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A), thromboxane A synthase 1, platelet, thromboxane synthase, thromboxane-A synthase, TS, TXA synthase, TXAS, TXS

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21391, 6916

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot, Immunohistochemistry, Western Blot

Concentration

1.15 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P24557, P36423

Gene Symbols

TBXAS1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 355-534 of human Thromboxane synthase (NP_0010522)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: TYLLATNPDC QEKLLREVDV FKEKHMAPEF CSLEEGLPYL DMVIAETLRM YPPAFRFTRE AAQDCEVLGQ RIPAGAVLEM AVGALHHDPE HWPSPETFNP ERFTAEARQQ HRPFTYLPFG AGPRSCLGVR LGLLEVKLTL LHVLHKFRFQ ACPETQVPLQ LESKSALGPK NGVYIKIVSR; Positive Samples: THP-1, A-549, NCI-H460; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein Thromboxane synthase encodes a member of the cytochrome P450 superfamily of enzymes
  • The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids
  • However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity
  • This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation
  • The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke
  • Alternatively spliced transcript variants encoding different isoforms have been found for this gene.