Thrombopoietin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595945-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595945 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Thrombopoietin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
THPO
Gene Alias
C-mpl ligand, Megakaryocyte colony-stimulating factor, megakaryocyte growth and development factor, megakaryocyte stimulating factor, Mgdf, MKCSF, ML, MPL ligand, Mpllg, MSA, Myeloproliferative leukemia virus oncogene ligand, prepro-thrombopoietin, TDH2A, THCYT1, THPO, Thrombopoietin, thyroid microsomal antigen, thyroid peroxidase, thyroperoxidase, Tpo, TPX
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
108348162, 21832, 7066, 81811
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.48 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P40225, P40226, P49745
Gene Symbols
THPO
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-349 of human THPO (NP_0011710681)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QGRTTAHKDP NAIFLSFQHL LRGKVRFLML VGGSTLCVRR APPTTAVPSR TSLVLTLNEL PNRTSGLLET NFTASARTTG SGLLKWQQGF RAKIPGLLNQ TSRSLDQIPG YLNRIHELLN GTRGLFPGPS RRTLGAPDIS SGTSDTGSLP PNLQPGYSPS PTHPPTGQYT LFPLPPTLPT PVVQLHPLLP DPSAPTPTPT SPLLNTSYTH SQNLSQEG; Positive Samples: MCF7, U-937, BT-474 Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage
- Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, μgtimately, to the production of platelets (thrombopoiesis)
- Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.