PIPA592174

NAE1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA592174-Each-of-1 In Stock ₹ 46,502.50

PIPA592174 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

NAE1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NAE1

Gene Alias

59kDa, A-116A10.1, amyloid beta precursor protein binding protein 1, 59kDa, amyloid beta precursor protein-binding protein 1, 59 kDa, amyloid beta precursor protein-binding protein 1, 59kD, amyloid protein-binding protein 1, Appbp1, APP-BP1, HPP1, Nae1, NEDD8 activating enzyme E1 subunit 1, NEDD8-activating enzyme E1 regulatory subunit, NEDD8-activating enzyme E1 subunit, protooncogene protein 1, proto-oncogene protein 1, μga-1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

234664, 84019, 8883

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.59 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

Q13564, Q8VBW6, Q9Z1A5

Gene Symbols

NAE1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NAE1 (NP_0038961)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MAQLGKLLKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV LPGIGSFTII DGNQVSGEDA GNNFFLQRSS IGKNRAEAAM EFLQELNSDV SGSFVEESPE NLLDNDPSFF CRFTVVVATQ LPESTSLRLA DVLWNSQIPL LICRTYGLVG YMRIIIKEHP VIESHPDNAL EDLRLDKPFP ELREHFQSYD LDHMEKKDHS HTPWIVIIAK; Positive Samples: SH-SY5Y, BT-474, HL-60, SW620, NIH/3T3, Mouse brain, Mouse lung, Rat brain; Cellular Location: Cell membrane The protein encoded by this gene binds to the beta-amyloid precursor protein
  • Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease
  • In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein
  • This protein is required for cell cycle progression through the S/M checkpoint
  • Three transcript variants encoding different isoforms have been found for this gene.