Neuropilin-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595832-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595832 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Neuropilin-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NRP1
Gene Alias
A5 protein, BDCA4, C530029I03, CD304, Neuropilin, neuropilin 1, Neuropilin1, neuropilin-1, Neuropilin-1 precursor (A5 protein), NP1, NP-1, Npn1, NPN-1, NRP, NRP 1, Nrp1, sNRP 1, sNRP1, soluble NRP 1, soluble NRP1, transmembrane receptor, vascular endothelial cell growth factor 165 receptor, VEGF165R
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18186, 246331, 8829
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.50 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
O14786, P97333, Q9QWJ9
Gene Symbols
NRP1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 824-923 of human Neuropilin-1 (NRP1) (NP_0038645)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: SH-SY5Y, A-549, U-87MG, 293T, mouse brain; Cellular Location: Cell membrane, Single-pass type I membrane protein Immunogen sequence: FELVDGVKLK KDKLNTQSTY SEA Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain
- Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors
- Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system
- This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis
- Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.