Thermo Scientific™ Tango™ AGTR1-blaU2OS Cells
Manufacturer: Thermo Scientific™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1443-Each-of-1 | In Stock | ₹ 9,41,620.00 |
K1443 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,41,620.00
GST (18%): ₹ 1,69,491.60
Total Price: ₹ 11,11,111.60
Accession Number
NM_032049.2
Cell State
Dividing Cells
Cytoplasmic Tail
Native Tail
For Use With (Application)
FRET
Human Protein Class
G-Protein Coupled Receptor (GPCR)
Product Line
Tango™
Readout
End Point
Target Entry
AGTR1
System Type
Tango™
Assay Entry
Cell-based beta-arrestin recruitment
Content And Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ AGTR1-UAS-bla CHO-K1 cells• Tango™ AGTR1-UAS-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe Tango™ AGTR1-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method
Fluorescence
Gene Symbol
AGTR1
Population Status
Single Cell Clone Origin
Quantity
8 x 106Cells
Shipping Condition
Room Temperature
Cell Line
U2OS
Druggable Target
GPCR
Related Products
Description
- Tango™ AGTR1-bla U2OS cells contain the human Angiotensin Receptor 1 (AGTR1) (AGTR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
- This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element
- The Tango™ AGTR1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Angiotensin II (Figure 1)
- In addition, Tango™ AGTR1-bla U2OS cells have been tested for assay performance under variable conditions.