700077P
FF-MAS
Manufacturer: Sigma Aldrich
CAS Number: 64284-64-6
Synonym(S): 14-demethyl-14-dehydrolanosterol, 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol; follicular fluid meiosis-activating sterol
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 700077P-1-MG | In Stock | ₹ 1,02,339.55 |
700077P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 1,02,339.55
GST (18%): ₹ 18,421.119
Total Price: ₹ 1,20,760.669
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700077P-1mg)
manufacturer/tradename
Avanti Polar Lipids
shipped in
dry ice
storage temp.
−70°C
InChI
1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1
InChI key
LFQXEZVYNCBVDO-PBJLWWPKSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
64284-64-6 | (3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol | -- | ₹ 71,111.00 |
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Description
- General description: Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in the cholesterol biosynthetic pathway present in all cells, and may represent the physiological signal that instructs the oocyte to reinitiate meiosis.
- Application: FF-MAS has been used:as a standard in gas chromatography/ mass spectroscopy (GC/MS) for profiling sterols of oligodendrocyte progenitor cells (OPCs)[1]as Dulbecco′s modified eagle medium (DMEM) medium supplement to test its effect on cancer cell viability[2]to evaluate its effect on LXRβ-overexpressing squamous carcinoma SCC61 cells[3]
- Biochem/physiol Actions: 14-demethyl-14-dehydrolanosterol (FF-MAS) was first identified in follicular fluid of women and plays a key role in oocyte nuclear maturation.[4] The levels of FF-MAS may be regulated by cytochrome P450 family 27 subfamily A member 1.[5] Supplementation of FF-MAS to oocytes promotes meiotic maturation favoring preimplantation. However, FF-MAS has low solubility and is metabolized to cholesterol rapidly.[6]
- Packaging: 5 mL Amber Glass Screw Cap Vial (700077P-1mg)