860508P
C8 Ceramide (d18:1/8:0)
Manufacturer: Sigma Aldrich
CAS Number: 74713-59-0
Synonym(S): N-octanoyl-D-erythro-sphingosine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 860508P-5-MG | In Stock | ₹ 12,557.00 |
860508P - 5 MG
In Stock
Quantity
1
Base Price: ₹ 12,557.00
GST (18%): ₹ 2,260.26
Total Price: ₹ 14,817.26
form
powder
packaging
pkg of 1 × 5 mg (860508P-5mg)
manufacturer/tradename
Avanti Polar Lipids 860508P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1
InChI key
APDLCSPGWPLYEQ-WRBRXSDHSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Enzo Life Sciences C8 Ceramide (25 mg). CAS: 74713-59-0 | -- | ₹ 32,649.65 | ||
eMolecules Medchem Express / C8-Ceramide / 5mg / 572596471 / HY-108391 / / 74713-59-0 / MFCD00236496 / 425.698 / C26H51NO3 | -- | ₹ 9,170.56 | ||
74713-59-0 | Octanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]- | -- | ₹ 1,780.00 - ₹ 17,622.00 |
Related Products
Description
- General description: C8 Ceramide is a short chain ceramide and is cell permeable.[1]
- Application: C8 Ceramide (d18:1/8:0) has been used as an internal ceramide standard in electrospray ionization.[2] It has also been used as a substrate for ceramide kinase activity assay.[3] It is suitable for use as a substrate for galactocerebrosidase.[4]
- Biochem/physiol Actions: C8 Ceramide has anti-tumor functionality.[1] Synthetic liposomal C8 ceramide inhibits hepatocellular carcinoma (HCC).[1] Addition of exogenous C8 ceramide causes necrosis in hepatocytes by decreasing ATP levels and impairing mitochondrial functionality.[5] C8 ceramide inhibition of serine palmitoyl transferase halts de novo sphingolipid biosynthesis.[6] It also acts as chemotherapeutic agent by increasing the reactive oxygen species in lung cancer cells.[7]
- Packaging: 5 mL Amber Glass Screw Cap Vial (860508P-5mg)