7161690
Tocris Bioscience™ uPSEM 817 tartrate
Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
Manufacturer: Fischer Scientific
CAS Number: 2341833-14-3
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Chemical Name or Material
2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate
Target
Pharmacologically Selective Effector Molecules/PSEM
Formula Weight
419.43
CAS
2341833-14-3
Molecular Formula
C16H19N3O.C4H6O6
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ uPSEM 817 tartrate | -- | ₹ 1,06,622.00 | ||
Tocris Bioscience™ uPSEM 817 tartrate | -- | ₹ 27,812.50 |
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Description
- Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channels (EC50 values are 0.3 and 0.5 nM, respectively)
- Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices
- Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C