01-674-190
BACE2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-190-Each-of-1 | In Stock | ₹ 46,814.00 |
01-674-190 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,814.00
GST (18%): ₹ 8,426.52
Total Price: ₹ 55,240.52
Antigen
BACE2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BACE2
Gene Alias
BACE2, AEPLC, ALP56, ASP1, ASP21, BAE2, CDA13, CEAP1, DRAP, beta secretase 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
25825, 288227, 56175
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q9Y5Z0, Q9JL18, Q6IE75
Gene Symbols
BACE2
Immunogen
Synthetic peptide corresponding to residues 44-59 of human BACE2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In Western blot, this antibody detects a ∽70 kDa band in human heart tissue lysate
- BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP)
- BACE2 cleaves APP between residues 690 and 691
- This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP
- BACE2 is also know to cleave APP between residues 671 and 672
- Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.