SIRT3 Monoclonal Antibody (C3), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
SIRT3
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
2310003L23Rik, AI848213, HGNC:14931, hSIRT3, mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase, mitochondrial protein lysine deacetylase, mSIR2L3, NAD-dependent deacetylase sirtuin-3, NAD-dependent deacetylase sirtuin-3, mitochondrial, NAD-dependent protein deacetylase sirtuin-3, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, regulatory protein SIR2 homolog 3, silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3, silent mating type information regulation 2, S.cerevisiae, homolog 3, Sir2l3, sir2-like 3, SIR2-like protein 3, SIRT3, SIRT3L mitochondrial, sirtuin 3, sirtuin type 3
Gene Symbols
SIRT3
Isotype
IgG1 κ
Purification Method
Protein A/G
Gene
SIRT3
Clone
C3
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Porcine
Gene Accession No.
Q9NTG7
Gene ID (Entrez)
100125971, 23410
Immunogen
Recombinant Human SIRT3 protein, Gln126-Lys399 (Accession #Q9NTG7)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein
- Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes
- The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA
- Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity
- The SIRT3 is included in class I of the sirtuin family.