TIGIT Monoclonal Antibody (D3), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TIGIT
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
ENSMUSG00000071552, T cell immunoreceptor with Ig and ITIM domains, T-cell immunoreceptor with Ig and ITIM domains, TIGIT, V-set and immunoglobulin domain containing 9, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain containing 3, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3, Washington University cell adhesion molecule, WUCAM
Gene Symbols
TIGIT
Isotype
IgG1 κ
Purification Method
Protein A/G
Gene
TIGIT
Clone
D3
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q495A1
Gene ID (Entrez)
201633
Immunogen
Recombinant Human TIGIT protein, Gly21-Leu234 (Accession #Q495A1)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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Description
- Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.