4559180
Epredia™ Lab Vision™ Progesterone Receptor Rabbit Monoclonal Antibody
Progesterone Receptor, Rabbit Monoclonal Antibody is part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.
Manufacturer: Fischer Scientific
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Antigen
Progesterone Receptor (SP2)
Classification
Monoclonal
Host Species
Rabbit
Research Discipline
Cancer and Tumor Biology
Primary or Secondary
Primary
Clone
SP2
Conjugate
Unconjugated
Regulatory Status
IVD
Immunogen
Recombinant protein encoding human progesterone receptor 412-526 aa
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Description
- The progesterone receptor (PgR) is an estrogen-regulated protein
- It has been proposed that expression of PgR determination indicates a responsive estrogen receptor (ER) pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer
- A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival
- PgR has proved superior to ER as a prognostic indicator in some studies
- Host Species: Rabbit Clone: SP2 Isotype: IgG Species Reactivity: Human
- Others not tested
- Epitope: 412-526aa Immunogen: Recombinant protein encoding human progesterone receptor 412-526aa Molecular Weight: 116 + 81kDa Positive Control: Breast CA, T47D cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting