7143989

DNA-PKcs Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

DNA-PKcs

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

DNA-dependent protein kinase catalytic subunit

Gene Symbols

PRKDC

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P78527

Gene ID (Entrez)

5591

Immunogen

Between 2100 and 2150

Primary or Secondary

Primary

Content And Storage

4° C

Gene

PRKDC

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Monkey, Northern white-cheeked gibbon and Crab-eating macaque The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK)
  • The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q
  • On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.