7144056
MSH6 Polyclonal Antibody, Bethyl Laboratories
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MSH6
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
GTBP, HNPCC5, HSAP
Gene Symbols
MSH6
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Goat
Target Species
Human
Gene Accession No.
P52701
Gene ID (Entrez)
2956
Immunogen
Between 350 and 400
Primary or Secondary
Primary
Content And Storage
4° C
Gene
MSH6
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Gorilla, Chimpanzee and Northern white-cheeked gibbon Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome)
- HNPCC is an autosomal, domitly inherited disease associated with marked increase in cancer susceptibility
- it is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts
- HNPCC is reported to be the most common form of inherited colorectal cancer in the western world
- MSH6 is central to mismatch DNA repair.