7143982

MCM3 Polyclonal Antibody, Bethyl Laboratories

Goat Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

MCM3

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

HCC5, MGC1157, P1-MCM3, P1.h, RLFB

Gene Symbols

MCM3

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Goat

Target Species

Human

Gene Accession No.

P25205

Gene ID (Entrez)

4172

Immunogen

Between 500 and 550

Primary or Secondary

Primary

Content And Storage

4° C

Gene

MCM3

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Horse, Pig, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Crab-eating The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are involved in the initiation of eukaryotic genome replication
  • The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins
  • This protein is a subunit of the protein complex that consists of MCM2-7
  • It has been shown to interact directly with MCM5/CDC46
  • This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase
  • The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.