7144175
PolD3/p66 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PolD3/p66
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
DNA polymerase delta subunit 3, DNA polymerase delta subunit p66, POLD3, KIAA0039, DNA pol delta3, DNA pol delta3, DNApol delta3, DNA pol delta p66, DNA pol delta p66
Gene Symbols
POLD3
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q15054
Gene ID (Entrez)
10714
Immunogen
Between 325 and 375
Primary or Secondary
Primary
Content And Storage
4° C
Gene
POLD3
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Monkey, Chimpanzee, Northern white-cheeked gibbon and Crab-eating macaque DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases
- In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches
- These exonucleases include the family of DNA polymerases, namely DNA pol alpha, beta, delta and epsilon
- DNA pol delta and DNA pol epsilon are multisubunit enzymes, with DNA pol delta consisting of two subunits which interact with the sliding DNA clamp protein PCNA
- DNA pol delta 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol delta.