MMSET / WHSC1 Monoclonal Antibody (29D1), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MMSET / WHSC1
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
5830445G22Rik; 9430010A17Rik; AW555663; C130020C13Rik; D030027O06Rik; D930023B08Rik; Histone-lysine N-methyltransferase NSD2; IL5 promoter REII region-binding protein; KIAA1090; mKIAA1090; MMSET; multiple myeloma SET domain containing protein type III; Multiple myeloma SET domain-containing protein; NSD2; nuclear receptor binding SET domain protein 2; Nuclear SET domain-containing protein 2; probable histone-lysine N-methyltransferase NSD2; Protein trithorax-5; REIIBP; RGD1565590; trithorax/ash1-related protein 5; TRX5; WHS; WHSC1; Whsc1l; Wolf-Hirschhorn syndrome candidate 1; Wolf-Hirschhorn syndrome candidate 1 (human); Wolf-Hirschhorn syndrome candidate 1 protein; Wolf-Hirschhorn syndrome candidate 1 protein homolog
Gene Symbols
NSD2
Isotype
IgG2b
Purification Method
Protein G
Product Type
Antibody
Clone
29D1
Applications
ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
O96028
Gene ID (Entrez)
7468
Immunogen
This MMSET / WHSC1 antibody was raised against a recombinant protein corresponding to amino acids 1-647 of human MMSET-I.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
NSD2
Related Products
Description
- This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger
- It is expressed ubiquitously in early development
- Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4
- This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas
- Alternative splicing of this gene results in multiple transcript variants encoding different isoforms
- Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.