7188493

N6-Methyladenosine (m6A) Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

N6-Methyladenosine (m6A)

Applications

Dot Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Multi-species, Mouse, Rat

Immunogen

This antibody was raised against 6-Methyladenosine conjugated to kLH.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype

IgG

Purification Method

Protein A

Product Type

Antibody

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Description

  • N6-methyladenosine (m6A), or methylation of the N6 position of adenosine is a posttranscriptional modification of RNA
  • Due to a lack of analytical methods, N6-methyladenosine is poorly understood, but new evidence suggests that it is a very common base modification and important physiological regulator
  • N6-methyladenosine is markedly increased throughout brain development, and is enriched near stop codons, microRNA-binding sites and UTRs, which indicates a fundamental role in the regulation of gene expression
  • N6-methyladenosine is also highly conserved between human and mouse.