7188671
5-Formylcytosine (5-fC) Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
5-Formylcytosine (5-fC)
Applications
Dot Blot
Conjugate
Unconjugated
Host Species
Rabbit
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Isotype
IgG
Purification Method
Protein A
Product Type
Antibody
Concentration
1 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Immunogen
This 5-Formylcytosine antibody was raised against 5-formylcytidine conjugated to kLH and recognizes 5-formylcytosine.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Related Products
Description
- 5-formylcytosine is an oxidized derivative of 5-methylcytosine, a type of DNA methylation
- 5-formylcytosine is a nucleobase analogue with a cytosine that possesses a hydrogen at position 5 that has been replaced by a formyl group
- 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine
- These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family
- 5-formylcytosine has been shown to determine nucleosome organization and plays a role in regulating transcription.