Urokinase Recombinant Rabbit Monoclonal Antibody (10E5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549935-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA549935 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
Urokinase
Classification
Recombinant Monoclonal
Concentration
3.1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P00749
Gene Symbols
PLAU
Immunogen
A synthesized peptide derived from human Urokinase
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin)
Clone
10E5
Conjugate
Unconjugated
Gene
PLAU
Gene Alias
antagonist of uPA, ATF, BDPLT5, CD87, HGNC:9052, plasminogen activator, plasminogen activator, urinary, plasminogen activator, urokinase, Plau, QPD, uPA, u-PA, UPAM, UPAR, U-plasminogen activator, Urinary plasminogen activator, urokinase, URK, URKR, Urokinase-type plasminogen activator, Urokinase-type plasminogen activator chain B, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5328
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation
- A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding
- This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen
- Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain
- This two-chain derivative is also called HMW-uPA (high molecular weight uPA)
- HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment
- LMW-uPA is proteolytically active but does not bind to the uPA receptor
- Alternatively spliced transcript variants encoding different isoforms have been found for this gene.