SNTB2 Monoclonal Antibody (1351), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA1745-Each-of-1 | In Stock | ₹ 50,196.00 |
MA1745 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,196.00
GST (18%): ₹ 9,035.28
Total Price: ₹ 59,231.28
Antigen
SNTB2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
Q13425, Q61235
Gene Symbols
SNTB2
Immunogen
Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Amphibian, Canine, Chicken, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
1351
Conjugate
Unconjugated
Gene
SNTB2
Gene Alias
59 kDa dystrophin-associated protein A1 basic component 2; beta-2-syntrophin; D16S2531E; dystrophin-associated protein A1, 59kD, basic component 2; EST25263; Snt2; SNT2B2; SNT3; SNTB2; SNTL; SYN; syntrophin beta 2; syntrophin, basic 2; syntrophin, beta 2; syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2); syntrophin-3; Syntrophin-like
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
20650, 479675, 6645, 689421, 769654
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-745 detects alpha 1, beta 1 and beta 2 subunits of syntrophin
- This antibody has been shown to react with human, mouse, rat, chicken, canine and amphibian samples
- MA1-745 has been successfully used in Western blot, immunoprecipitation and immunofluorescence procedures
- By Western blot, this antibody detects an ∽58 kDa protein representing syntrophin from rat and mouse cell extracts
- The MA1-745 immunogen is whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane
- Characterization studies of this antibody have demonstrated that clone 1351 is directed against an epitope within the PDZ domain of syntrophin
- MA1-745, clone 1351, is seen as the gold standard for syntrophin assessment
- Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation
- To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2
- These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2)
- The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex
- This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.