PPAR alpha Monoclonal Antibody (3B6/PPAR), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA1822-Each-of-1 | In Stock | ₹ 48,282.50 |
MA1822 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,282.50
GST (18%): ₹ 8,690.85
Total Price: ₹ 56,973.35
Antigen
PPAR alpha
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P23204, P37230, Q07869
Gene Symbols
PPARA
Immunogen
Purified recombinant PPAR alpha protein.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2b
Applications
ChIP Assay, Flow Cytometry, Gel Shift, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
3B6/PPAR
Conjugate
Unconjugated
Gene
PPARA
Gene Alias
4933429D07Rik; AW742785; hPPAR; I79_022392; MGC2237; MGC2452; Nr1c1; nuclear hormone receptor; nuclear receptor; nuclear receptor subfamily 1 group C member 1; peroxisome proliferative activated receptor alpha; peroxisome proliferative activated receptor, alpha; peroxisome proliferative activated receptor, alpha isoform 1; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor alpha; peroxisome proliferator-activated nuclear receptor alpha variant 3; peroxisome proliferator-activated receptor alpha; PPAR; PPAR ALPHA; Ppara; PPARALPHA; PPAR-alpha; proliferator-activated receptor alpha; transcription factor belonging to the nuclear receptor superfamily
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
19013, 25747, 5465
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-822 detects peroxisome proliferator activated receptors (PPAR) alpha from human, mouse, and rat tissues
- MA1-822 has been successfully used in Western blot, Gel Shift and immunoprecipitation procedures
- By Western blot, this antibody detects a ∽52 kDa protein which corresponds to PPAR alpha from mouse adipose tissue extract
- This antibody detects some non-specific bands on NIH-3T3 cell lysates
- The MA1-822 immunogen is purified recombinant PPAR alpha protein
- Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPAR's)
- Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand
- Studies indicate that PPAR's are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids
- It has also been shown that PPAR's can induce transcription of acyl coenzyme A oxidase & cytochrome P450 (CYP450) A6 through interaction with specific response elements
- PPAR, like several other nuclear hormone receptors, heterodimerizes with retinoid X receptor (RXR) alpha.