Triadin Monoclonal Antibody (GE 4.90), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3927-Each-of-1 | In Stock | ₹ 42,586.50 |
MA3927 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,586.50
GST (18%): ₹ 7,665.57
Total Price: ₹ 50,252.07
Antigen
Triadin
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.05% sodium azide
Gene Accession No.
E9Q9K5, Q28820, Q9QX75
Gene Symbols
TRDN
Immunogen
Purified rabbit fast skeletal muscle triadin.
Regulatory Status
RUO
Gene ID (Entrez)
100009519, 59299, 76757
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone
GE 4.90
Conjugate
Unconjugated
Gene
TRDN
Gene Alias
2310045H21Rik; cardiac triadin; cardiac triadin isoform 1; cardiac triadin isoform 2; cardiac triadin isoform 3; CPVT5; EG432451; junctional sarcoplasmic reticulum glycoprotein; TDN; Trdn; Triadin; triadin 1; triadin 32 kDa (TRISK 32); triadin 49 kDa (TRISK 49); triadin 95; TRISK
Host Species
Mouse
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Mouse, Rabbit, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- MA3-927 detects triadin from mouse, rabbit and rat tissues
- MA3-927 has been successfully used in Western blot, immunohistochemistry, immunoprecipitation and ELISA procedures
- By Western blot, this antibody detects a 95 kDa protein representing triadin from rabbit skeletal muscle extracts
- Immunohistochemical staining of triadin in rat skeletal muscle with MA3-927 results in striated staining consistent with sarcoplasmic reticulum localization
- The MA3-927 antigen is purified rabbit fast skeletal muscle triadin
- The junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad
- At the triad, dihydropyridine receptors (DHPR’s) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR’s), the calcium release channels, exist in the membrane of the terminal cisternae of the SR
- It is thought that during slow phase depolarization of the T-tubule, a third protein, triadin (MW 95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR’s and RyR’s
- Though its exact role in this signaling process is unclear, triadin has been shown to co-localize with both DHPR and RYR at the junctional face of the terminal cisternae.