MABE461MI
MilliporeSigma™ Mouse anti-CRTC1, Clone: 5F3.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE461MI-Each-of-1 | In Stock | ₹ 41,813.98 |
MABE461MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,813.98
GST (18%): ₹ 7,526.516
Total Price: ₹ 49,340.496
Antigen
CRTC1
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
CRTC1; KIAA0616; MECT1; TORC1; WAMTP1
Immunogen
GST-tagged recombinant protein corresponding to human CRTC1/TORC-1 sequence within the N-terminal half..
Quantity
100 μg
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_001091952
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2a κ
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
5F3.1
Gene Accession No.
Q6UUV9
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
Related Products
Description
- Specifically detects CRTC1 clone: 5F3.1 in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry, Immunoprecipitation, Western Blotting CREB-regulated transcription coactivator 1 (UniProt Q6UUV9; also known as Mucoepidermoid carcinoma translocated protein 1, TORC-1, Transducer of CREB protein 1, Transducer of regulated cAMP response element-binding protein 1) is encoded by the CRTC1 (also known as KIAA0616, MECT1, TORC1, WAMTP1) gene (Gene ID 23373) in human
- CRTC1 belongs to a family of glycosylated Ser/Thr-rich phosphoproteins that bind the basic leucine zipper (bZIP) region of Ca 2+ /cAMP-responsive element-binding protein (CREB) and function as CREB coactivators
- CRTCs participate in CREB-mediated transcriptions of both canonical cellular cAMP response elements (CREs) and the non-canonical viral CREs
- CRTC1, specifically, is involved in CREB-mediated transcription of various neuronal immediate early genes (IEGs) as well as CREB-dependent hepatitis B virus (HBV) replication.