MABN794MI
MilliporeSigma™ Mouse anti-GLAST, Clone: 8C11.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN794MI-Each-of-1 | In Stock | ₹ 41,813.98 |
MABN794MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,813.98
GST (18%): ₹ 7,526.516
Total Price: ₹ 49,340.496
Antigen
GLAST
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1λ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
SLC1A3; EAAT1; GLAST; GLAST1
Immunogen
GST-tagged recombinant protein corresponding to the extracellular domain of human GLAST.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_004163
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 λ
Applications
Immunohistochemistry, Western Blot
Clone
8C11.1
Gene Accession No.
P43003
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Purified
Related Products
Description
- Specifically detects GLAST clone: 8C11.1 in Human, Rat samples, and it is validated for Immunohistochemistry, Western Blotting Excitatory amino acid transporter 1 (UniProt P43003; also known as GLAST-1, Sodium-dependent glutamate/aspartate transporter 1, Solute carrier family 1 member 3) is encoded by the SLC1A3 (also known as EA6, EAAT1, GLAST, GLAST1) gene in human (Entrez Gene ID 6507)
- GLAST-1 is a multitransmembrane protein that functions as a high affinity glutamate transporter and mediates the termination of postsynaptic action of glutamate in central nervous system by rapidly removing released glutamate from the synaptic cleft
- GLAST-1 also transports L- and D-aspartate
- GLAST gene mutations are linked to episodic ataxia type 6 (EA6), a disorder characterized by seizures, migraine, and alternating hemiplegia
- There are 5 known spliced variants
- Isoform 2 has no functional glutamate uptake activity and exerts a dominant negative effect against isoform 1.