MABT327MI
MilliporeSigma™ Mouse anti-DDR1 (CD167a), Clone: 48B3,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT327MI-Each-of-1 | In Stock | ₹ 40,762.00 |
MABT327MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,762.00
GST (18%): ₹ 7,337.16
Total Price: ₹ 48,099.16
Antigen
DDR1 (CD167a)
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Symbols
DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Immunogen
Whole cells corresponding to human DDR1 (CD167a).
Quantity
200 μL
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001189450
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgM κ
Applications
Functional Assay, Flow Cytometry
Clone
48B3
Gene Accession No.
Q08345
Host Species
Mouse
Purification Method
Purified by Ion-Exchange Chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects DDR1 (CD167a) clone: 48B3 in Human samples, and it is validated for Activity Assay, Flow Cytometry Epithelial discoidin domain-containing receptor 1 (DDR1) is a receptor tyrosine kinase that functions as a cell surface receptor for fibrillar collagen and ultimately regulates cellular responses that involve ECM and ECM remodeling, cell migration, differentiation, survival, wound healing and proliferation
- DDR1 is also required for normal development of everything from mammary function to hearing
- DDR1 also plays a key role in tumor cell migration and invasion
- DDR1 is expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney
- Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas
- DDR1 is abundant in breast carcinoma and other cancer cell lines, but DDR1 is not expressed in the connective tissue of the gut lamina propria other connective tissues, endothelial cells, adipose tissue, muscle cells or cells of hematopoietic origin.