PA1057

PCSK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1057-Each-of-1 In Stock ₹ 45,968.50

PA1057 - Each of 1

₹ 45,968.50

In Stock

Quantity

1

Base Price: ₹ 45,968.50

GST (18%): ₹ 8,274.33

Total Price: ₹ 54,242.83

Antigen

PCSK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PCSK1

Gene Alias

Att-1; Bdp; BMIQ12; EC 3.4.21.93; Furin homolog; LOW QUALITY PROTEIN: neuroendocrine convertase 1; NEC 1; NEC1; Nec-1; Neuroendocrine convertase 1; PC1; PC3; PCSK1; Phpp-1; Prohormone convertase 1; prohormone convertase 1/3; prohormone convertase 3; propeptide-processing protease; Proprotein convertase 1; proprotein convertase subtilisin/kexin type 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I; SPC3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18548

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P63239

Gene Symbols

PCSK1

Immunogen

Synthetic peptide corresponding to residues S(111) V Q K D S A L D L F N D P M W N(127) of mouse PC1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PA1058

--

Img

Thermo Scientific

MA1-413

--

Img

Thermo Scientific

PA11051

--

Img

Thermo Scientific

PA128462

--

Img

Thermo Scientific

PA1055

--

Img

Thermo Scientific

PA1015

--

Img

Thermo Scientific

PA1020

--

Img

Thermo Scientific

PA1080

--

Description

  • PA1-057 detects prohormone convertase 1 (PC1) from mouse pituitary extract
  • PA1-057 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽80 kDa protein representing PC1 from mouse pituitary extract
  • The PA1-057 immunogen is a synthetic peptide corresponding to residues S(111) V Q K D S A L D L F N D P M W N(127) of mouse PC1
  • This sequence is 88% and 82% conserved bovine and rat, respectively
  • The PA1-057 immunizing peptide (Cat
  • # PEP-164) is available for use in neutralization and control experiments
  • The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family
  • The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products
  • This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis
  • It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin
  • Mutations in this gene are thought to cause obesity
  • This encoded protein is associated with carcinoid tumors
  • The use of alternate polyadenylation sites has been found for this gene
  • Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known.