UCP3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1055-Each-of-1 | In Stock | ₹ 48,015.50 |
PA1055 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,015.50
GST (18%): ₹ 8,642.79
Total Price: ₹ 56,658.29
Antigen
UCP3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ucp3
Gene Alias
AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22229, 25708, 403575
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P56499, P56501, Q9N2I9
Gene Symbols
Ucp3
Immunogen
Synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UCP-3.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Canine, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-055 detects uncoupling protein-3 (UCP-3) mouse, rat, and canine tissues
- This antibody will also detect recombinant human UCP-3, but does not detect UCP-3 from mouse liver or kidney
- PA1-055 has been successfully used in Western blot procedures
- By Western blot, this antibody detects an ∽30 kDa protein representing UCP-3 from rat heart homogenate
- The PA1-055 immunogen is a synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UPC-3
- This peptide differs from the porcine and human UCP-3 sequence by a single amino acid substitution
- PA1-055 immunizing peptide (Cat
- # PEP-074) is available for use in neutralization and control experiments
- The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria
- UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane
- This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism
- UCP2 is a structurally related protein that also uncouples mitochondrial respiration
- It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1
- UCP2 is thought to play a role in body weight regulation
- An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.