BMP-2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA131215-Each-of-1 | In Stock | ₹ 52,955.00 |
PA131215 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,955.00
GST (18%): ₹ 9,531.90
Total Price: ₹ 62,486.90
Antigen
BMP-2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BMP2
Gene Alias
2610024H22Rik; AI467020; AL117858; AW546137; BB189135; BDA2; BMP; BMP2; BMP-2; BMP2A; BMP-2A; BMPRII; BMPR-II; Bone morphogenetic protein; Bone morphogenetic protein 2; bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A); bone morphogenetic protein 2A; H-BMP-2; morphogen
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12156, 650
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.73 mg/mL
Formulation
tris glycine with 0.5% BSA, 30% glycerol and 0.02% sodium azide; pH 7.4-7.9
Gene Accession No.
P12643, P21274
Gene Symbols
BMP2
Immunogen
synthetic peptide SEDVLSEFELRLLSM conjugated to KLH, corresponding to amino acids 45-60 of BMP2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A band is detected around 45 kDa
- Bone Morphogenic Proteins (BMP) are members of the TGF-beta superfamily that affect bone and cartilage formation (Hogan 1996, Reddi 1998 and Francis-West et al
- 1999)
- Mature BMPs are 30-38 kDa proteins that assume a TGF-beta -like cysteine knot configuration
- Lovostatin increases bone formation by turning on the bmp-2 gene (Mundy et al
- 1999)
- BMPs stimulate the production of specific bone matrix proteins and alter stromal cell and osteoclast proliferation (Macias et al
- 1999, Lecanda et al
- 1997)
- BMPs may also be an important factor for development of the viscera, with roles in cell proliferation, apoptosis, differentiation, and morphogenesis (Hogan 1996, Dale and Wardle 1999)
- BMPs appear to be responsible for normal dorsal/ventral patterning
- Like TGF-beta, BMPs bind to a type II receptor, which then recruits the transducing type I receptor unit, activating the Smad protein signaling pathway (Massague 1994, Derynck 1997, Attisano 1993).