Lass4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA549881-Each-of-1 | In Stock | ₹ 46,057.50 |
PA549881 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
Lass4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CERS4
Gene Alias
2900019C14Rik; Ceramide synthase 4; CerS4; FLJ12089; LAG1 homolog, ceramide synthase 4; LAG1 longevity assurance homolog 4; Lass4; longevity assurance homolog 4; Sphingosine N-acyltransferase CERS4; TRAM homolog 1; translocating chain-associating membrane protein homolog 1; Trh1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
67260, 79603
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9D6J1, Q9HA82
Gene Symbols
CERS4
Immunogen
Synthesized peptide derived from internal of human LASS4.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total Lass4 protein
- The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals
- Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis
- LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein
- LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides
- In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.