Insulin/Proinsulin Monoclonal Antibody (D6C4 (5E4/3)), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA183255-Each-of-1 | In Stock | ₹ 55,269.00 |
PIMA183255 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,269.00
GST (18%): ₹ 9,948.42
Total Price: ₹ 65,217.42
Antigen
Insulin/Proinsulin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
P01308, P01315, P01317, P01322, P01323, P01325, P01326
Gene Symbols
INS, Ins1, Ins2
Immunogen
Recombinant human insulin
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunohistochemistry (Frozen)
Clone
D6C4 (5E4/3)
Conjugate
Unconjugated
Gene
INS
Gene Alias
AA986540; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2; Ins-2; Ins2-rs1; InsII; Insulin; insulin 1; insulin 2; Insulin A chain; Insulin B chain; insulin I; insulin II; insulin-1; Insulin-1 A chain; Insulin-1 B chain; Insulin-2; Insulin-2 A chain; Insulin-2 B chain; IRDN; Mody; MODY10; Mody4; preproinsulin; proinsulin
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16333, 16334, 24505, 24506, 280829, 3630, 397415
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product has an Affinity of 8.1x10^8 M^-1
- Mouse anti Human Insulin/Proinsulin antibody, clone D6C4 (5E4/3), recognizes both the pro and mature forms of human insulin but does not react with free C-peptide
- Insulin is a peptide hormone secreted by beta cells of the pancreatic islets
- It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions
- It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids
- Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin
- Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide
- Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population
- Insulin is also present in tumors of b-cell origin such as insulinoma.