PIMA515518

MUSK Monoclonal Antibody (10A4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515518-Each-of-1 In Stock ₹ 52,732.50

PIMA515518 - Each of 1

₹ 52,732.50

In Stock

Quantity

1

Base Price: ₹ 52,732.50

GST (18%): ₹ 9,491.85

Total Price: ₹ 62,224.35

Antigen

MUSK

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

O15146

Gene Symbols

MUSK

Immunogen

Purified recombinant extracellular fragment of human MUSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line.

Regulatory Status

RUO

Gene ID (Entrez)

4593

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

10A4

Conjugate

Unconjugated

Gene

MUSK

Gene Alias

CMS9; FADS; Mdk4; MGC126323; MGC126324; Mlk; muscle associated receptor tyrosine kinase; muscle localized kinase 2; muscle specific kinase (neural fold/somite kinase 1); muscle, skeletal receptor tyrosine protein kinase; Muscle, skeletal receptor tyrosine-protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; muscle-specific protein kinase secretory isoform; muscle-specific tyrosine kinase receptor MuSK; muscle-specific tyrosine protein kinase receptor; Muscle-specific tyrosine-protein kinase receptor; MuSK; Nsk1; Nsk2; Nsk3; RP23-170A3.1

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15518 targets MUSK in indirect ELISA, IF and IHC applications and shows reactivity with Human samples
  • The MA5-15518 immunogen is purified recombinant extracellular fragment of human MUSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line
  • MA5-15518 detects MUSK which has a predicted molecular weight of approximately 97kDa
  • MUSK plays an important and selective role in many aspects of skeletal muscle development and function through the initial step of postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn
  • Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells
  • Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor
  • MuSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintenance of the neuromuscular junction.