PIMA516025
Desmoglein 3 Monoclonal Antibody (5G11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516025-Each-of-1 | In Stock | ₹ 50,240.50 |
PIMA516025 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,240.50
GST (18%): ₹ 9,043.29
Total Price: ₹ 59,283.79
Antigen
Desmoglein 3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P32926
Gene Symbols
Dsg3
Immunogen
Human Desmoglein 3 recombinant protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Dot Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
5G11
Conjugate
Unconjugated
Gene
Dsg3
Gene Alias
130 kDa pemphigus vulgaris antigen; 130 kDa pemphigus vulgaris antigen homolog; bal; balding; Cadherin family member 6; CDHF6; desmoglein 3; desmoglein-3; DKFZp686P23184; Dsg3; PVA
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
1830
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Desmoglein 3 (Dsg3), also known as Cadherin family member 6 (CDHF6), is a member of the desmosomal cadherin family and plays a critical role in cell-cell adhesion
- It is predominately expressed in stratified squamous epithelium, including the skin, oral mucosa, and esophagus
- Desmoglein 3 has been characterized as the auto-antigen of pemphigus vulgaris (PV), a life-threatening autoimmune disease
- Binding of anti-Desmoglein 3 autoantibodies causes the loss of cell-cell adhesion, which clinically manifests as blisters on the skin and oral mucosa, and histologically as suprabasilar acantholysis.