AFP Monoclonal Antibody (SP154), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516321-Each-of-1 | In Stock | ₹ 55,714.00 |
PIMA516321 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,714.00
GST (18%): ₹ 10,028.52
Total Price: ₹ 65,742.52
Antigen
AFP
Classification
Monoclonal
Concentration
0.237 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.
P02771
Gene Symbols
AFP
Immunogen
Purified human AFP
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
SP154
Conjugate
Unconjugated
Gene
AFP
Gene Alias
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
174
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
- A suggested positive control is hepatocellular carcinoma or fetal liver
- AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life
- AFP expression in adults is often associated with hepatoma or teratoma
- However, hereditary persistence of AFP may also be found in individuals with no obvious pathology
- The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
- AFP is found in monomeric, dimeric, and trimeric forms
- AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin
- The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
- High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.