Phospho-PKC zeta (Thr560) Recombinant Rabbit Monoclonal Antibody (SN0753), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532326-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532326 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Phospho-PKC zeta (Thr560)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P09217, Q02956, Q05513
Gene Symbols
PRKCZ
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Thr560 of Human PKC zeta aa 531-580
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Clone
SN0753
Conjugate
Unconjugated
Gene
PRKCZ
Gene Alias
14 - 3 - 3 - zeta isoform, 14-3-3-zetaisoform, AI098070, aPKCzeta, atypical protein kinase C, C80388, kinase nPKC-zeta, KPCZ, nPKC-zeta, nPKC-zeta PRKCZ, PKC2, Pkcz, PKC-ZETA, Prkcz, protein kinase C zeta, protein kinase C zeta subspecies, protein kinase C zeta type, protein kinase C, zeta, r14-3-3, R74924, zetaPKC
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18762, 25522, 5590
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways
- In humans, at least 12 different PKC polypeptides have been identified
- These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
- PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
- PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.